PhD Student positions

Adult Neurogenesis in Pathogenesis and Treatment of neuropsychiatric symptoms in
neurodegeneration

Synucleinopathies are frequently accompanied by neuropsychiatric symptoms. There is
increasing evidence that impairment in adult hippocampal neurogenesis is linked to the
development of these symptoms. This project will use structural and behavioral analysis to
test whether restoration of neurogenesis will ameliorate behavior deficits in synucleinopathy
models. In addition, transcriptomic and bioinformatic analyses will be used to identify
mechanisms and candidate targets to restore neurogenesis / stem cell dependent plasticity.
The project will be conducted in a close collaboration between the Department of Molecular
Neurology (Head: Prof. Jürgen Winkler) and the Institute of Biochemistry (Research
Group Prof. Chichung Lie).
We are looking for highly motivated students with a Diploma/Master degree in
Molecular Medicine or Biology. Candidates should have a strong background in
Neurobiology, Cell Biology or Molecular Biology.
Starting date: October 2013 or later.
Applications should include a CV, references, and a research statement.
For further information please contact:
Professor Dr. Chichung Lie
Institute of Biochemistry
Friedrich Alexander University, Erlangen-Nuremberg
91054 Erlangen
Germany
Tel.: +49 (0)9131 85 24622
email: c.lie@biochem.uni-erlangen.de
http://www.biochem.uni-erlangen.de/forschung/arbeitsgruppe.php?arbeitsgruppe=5
Prof. Dr. med. Jürgen Winkler
Division of Molecular Neurology
Schwabachanlage 6
91054 Erlangen
Germany
Tel: +49 9131 85 39324
Email: juergen.winkler@uk-erlangen.de
http://www.molekulare-neurologie.uk-erlangen.de/e1585/index_ger.html