Se buscan candidatos para solicitar un contrato predoctoral

Estamos buscando candidatos para solicitar un contrato predoctoral para 
realizar una Tesis Doctoral enmarcada en el proyecto que se indica más 
adelante. La convocatoria saldrá a finales de Agosto, y la presentación 
de solicitudes se cerrará el 10 de Septiembre (ver BOE correspondiente 
en el enlace 
http://www.boe.es/boe/dias/2013/08/14/pdfs/BOE-A-2013-8984.pdf). Es 
necesario haber terminado, o estar finalizando, un Master Universitario 
(leer convocatoria para los requisitos necesarios). Las personas 
interesadas, con licenciatura de Biología, Química o Farmacia y 
preferentemente con expediente igual o superior a 2, contactar por 
e-mail con Fernando Rojo (e-mail: frojo@cnb.csic.es 
<mailto:frojo@cnb.csic.es>).

*TITULO DEL PROYECTO*: El sistema regulador formado por la proteína Crc 
y los sRNAs CrcZ y CrcY de /Pseudomonas putida/: nuevas funciones y 
control de CrcZ y CrcY
*Referencia del proyecto*: BFU2012-32797
*INVESTIGADOR PRINCIPAL: *Fernando Rojo de Castro**

*RESUMEN*: /Pseudomonas putida/ es una bacteria ubicua, metabólicamente 
muy versátil, y muy utilizada como modelo experimental y en 
biotecnología. Para entender su biología y para optimizar aplicaciones 
biotecnológicas basadas en esta bacteria, es importante conocer la redes 
de regulación global que coordinan la expresión de su genoma, y entender 
los mecanismos moleculares por los que funcionan estas redes. El 
objetivo de este proyecto es estudiar nuevos aspectos del sistema 
regulador formado por la proteína Crc y los RNAs pequeños (sRNAs) CrcZ y 
CrcY, responsable de una de estas redes de regulación, y entender cómo 
se controla su actividad. La proteína Crc es un regulador global que 
coordina y optimiza el metabolismo en las bacterias del género 
Pseudomonas, y tiene una función importante en el proceso de represión 
catabólica. Recientemente hemos demostrado que Crc actúa uniéndose a una 
diana presente en determinados mRNAs, inhibiendo su traducción. Datos 
recientes sugieren que, además de optimizar la asimilación de fuentes de 
carbono, Crc participa en otros procesos, coordinando diferentes 
aspectos de la fisiología de la bacteria. En este proyecto analizaremos 
la función de la proteína Crc en procesos que no se habían relacionado 
antes con este regulador, como la respuesta SOS o la síntesis de 
polihidroxialcanoatos (PHAs). Los PHAs son polímeros que la bacteria 
produce como sistema de reserva de carbono y energía, y para adaptar el 
flujo de carbono a la demanda de intermediarios metabólicos. Tienen 
propiedades similares a los plásticos y son biodegradables, lo que les 
da un gran interés biotecnológico. En /P. putida/,//la actividad de Crc 
está controlada por dos sRNAs llamados CrcZ y CrcY que pueden unirse a 
Crc y secuestrarla cuando su función no es necesaria. Por lo tanto, 
estos sRNAs actúan como antagonistas de Crc. Hemos observado que los 
niveles de CrcZ y CrcY varían fuertemente en función de señales 
fisiológicas y medioambientales, pero no se sabe cuál es el mecanismo 
responsable de estos cambios. Pretendemos averiguar si los niveles de 
CrcZ y CrcY se controlan regulando su transcripción, su degradación, o 
ambas cosas. También buscaremos los factores responsables de esta 
regulación. Los sRNAs han adquirido un protagonismo creciente y parece 
claro que tienen una función esencial en la regulación global de la 
expresión génica en bacterias, en especial para modular respuestas 
rápidas a cambios fisiológicos o medioambientales.

PhD Student positions

Adult Neurogenesis in Pathogenesis and Treatment of neuropsychiatric symptoms in
neurodegeneration

Synucleinopathies are frequently accompanied by neuropsychiatric symptoms. There is
increasing evidence that impairment in adult hippocampal neurogenesis is linked to the
development of these symptoms. This project will use structural and behavioral analysis to
test whether restoration of neurogenesis will ameliorate behavior deficits in synucleinopathy
models. In addition, transcriptomic and bioinformatic analyses will be used to identify
mechanisms and candidate targets to restore neurogenesis / stem cell dependent plasticity.
The project will be conducted in a close collaboration between the Department of Molecular
Neurology (Head: Prof. Jürgen Winkler) and the Institute of Biochemistry (Research
Group Prof. Chichung Lie).
We are looking for highly motivated students with a Diploma/Master degree in
Molecular Medicine or Biology. Candidates should have a strong background in
Neurobiology, Cell Biology or Molecular Biology.
Starting date: October 2013 or later.
Applications should include a CV, references, and a research statement.
For further information please contact:
Professor Dr. Chichung Lie
Institute of Biochemistry
Friedrich Alexander University, Erlangen-Nuremberg
91054 Erlangen
Germany
Tel.: +49 (0)9131 85 24622
email: c.lie@biochem.uni-erlangen.de
http://www.biochem.uni-erlangen.de/forschung/arbeitsgruppe.php?arbeitsgruppe=5
Prof. Dr. med. Jürgen Winkler
Division of Molecular Neurology
Schwabachanlage 6
91054 Erlangen
Germany
Tel: +49 9131 85 39324
Email: juergen.winkler@uk-erlangen.de
http://www.molekulare-neurologie.uk-erlangen.de/e1585/index_ger.html

Postdoc position

Postdoc position - PALM/STORM to study
S. pombe replication/genome stability
Full time, fixed term until 30 September 2016
Salary range: starting at £30,424 and rising to £36,298 per annum. It is normal to
appoint at the first point of the salary scale.
Closing date for applications: 21 August 2013 (can be flexible)
Expected start date: 1 October 2013
Description
An ERC-funded Postdoctoral Research Fellow position is immediately available in the
laboratory of Prof. Tony Carr to use PALM/STORM super-resolution microscopy to
study the mechanisms by which DNA replication is restarted following replication fork
collapse in fission yeast.
The aim of the project is to establish how replication is restarted when a
replication fork
becomes non-functional as a consequence of either DNA damage or replication blocks
imposed by DNA-protein interactions. Our recent data (Mizuno et al 2012, Nature
493:246-9) show that such restarted forks are error prone and we are exploring the
nature
and components of the restarted replication machinery using microscopy and classical
molecular studies.
Applicants must have a relevant PhD and a clear understanding of relevant microscopy
technologies. Previous experience of a range of molecular and cell biology techniques
and an interest in DNA replication are preferable attributes. The successful
candidate will
show evidence of successfully completing research projects.
Please contact: a.m.carr@siussex.ac.uk for more information.

PhD Position available (FPI fellowship) at CNIC-Spain

PhD Student Position

Fundación Centro Nacional de Investigaciones
Cardiovasculares Carlos III (CNIC)

PhD Position available (FPI fellowship) funded by the Ministry of Economy and Competitivity to work on a project (PI: Joan Isern) entitled “Unraveling The Ontogeny And Functions Of Embryonic Mesenchymal Stem/Progenitor Cells”.

TOPIC: Mammalian hematopoietic and cardiovascular development, focusing on the mesenchymal/stromal lineages.
This work utilizes various transgenic mouse models to dissect out the ontogeny and the contribution of mesenchymal progenitors to fetal hematopoiesis and cardiac organogenesis.
Interested applicants should submit their C.V. and names of two referees (before Sep 4th) to jisern@cnic.es
PhD Position available (FPI fellowship) funded by the Ministry of Economy and Competitivity to work on a project (PI: Joan Isern) entitled “Unraveling The Ontogeny And Functions Of Embryonic Mesenchymal Stem/Progenitor

Contrato de formación de personal investigador FPI en el Centro de Biología Molecular Severo Ochoa

Se oferta un contrato de formación de personal investigador FPI asociado al proyecto
del Plan Nacional METAGENÓMICA DE VIRUS EN PATOLOGÍAS FRECUENTES DE
LA CAVIDAD BUCAL (SAF2012-38421). La tesis se realizará en el Centro de Biología
Molecular Severo Ochoa, bajo la supervisión del doctor Alberto López Bueno
(http://web4.cbm.uam.es/joomla-rl/index.php/es/index.php?option=com_content&view=article&id=338).
Requisitos/criterios de selección: expediente académico superior a 2, experiencia previa
en Virología o Microbiología, manejo de herramientas bioinformáticas y programación,
motivación y capacidad de esfuerzo.
Los interesados deben enviar un CV actualizado con el expediente académico a
alopezbueno@cbm.uam.es antes del 31 de Agosto de 2013.

Alberto López Bueno PhD.
Universidad Autónoma de Madrid
Centro de Biología Molecular Severo Ochoa
C/ Nicolás Cabrera 1. 28049. Madrid
91 196 45 90
alopezbueno@cbm.uam.es

EU Marie-Curie Initial Training Network

EuTRiPD
European Training and Research in Peritoneal Dialysis
Call: FP7-PEOPLE-ITN-2011
Proposal Number: 287813
Vacancies: Marie Curie Early Stage Researcher (PhD) positions
Working-field
EuTRiPD is a European network in academic, public and private sectors that will provide a unique opportunity for a total of 12 researchers in early stages of their careers to study emerging research topics in the field of Peritoneal Dialysis and receive training to enhance their research skills, under the prestigious scheme of a Marie Curie Initial Training Network.
Your activities
You will work as PhD student at the Amsterdam EuTRiPD partner (others are Vienna, Poznan, Strasbourg, Cardiff, Heidelberg, Madrid, Berlin and Brussels). The research is all on different aspects of PD (in vitro studies; in vivo studies; clinical studies (data bank)). Every PhD student has their own project with the goal leading to a PhD thesis. Every six months the whole EuTRiPD group comes together for training and exchange in research at the institute of one of the EuTRiPD partners. Within the period of 36 months candidates also spend 4-6 months visiting one of the EuTRiPD collaborating partners and participate in a private sector secondment (ensuring intersectoral involvement).
Your profile
You have completed a study in biomedical science or medicine and are interested in a challenging PhD programme. You have no or less than four years working experience in research and are willing to work in a setting outside your home country.
Conditions of employment
Salary according European regulations for Adjunct-researchers there above a mobility allowance is given.
Duration: 20 months at Amsterdam EuTRiPD partner
This is a full-time position (hours differ per country)
Specialities
This position applies a “mobility” rule. The candidate must not have worked for more than
12 months in the country where he/she applies within the last three years. Furthermore, the candidate needs to be in the first four years of his/her research career. The four years are counted from the date the degree was obtained which formally entitles to embark on a doctorate.
At this moment a position is again available in Amsterdam for a period of 20 months per October 1st, 2013. The hired ESR will start in a running project that does research in anti-inflammatory intervention in a rat PD model as well as in human in vitro studies.
Interested
Information can be given by the coordinator of the project: Prof.dr. R.H.J. Beelen, Department of Molecular Cell Biology and Immunology (MCBI) VUmc tel. 020-4448055/8080, e-mail rhj.beelen@vumc.nl,
and/or the project manager Ms. T. van Wier, MCBI VUmc 020-4445513, e-mail t.vanwier@vumc.nl.
Starting date: 1 October 2013
You can directly apply for these vacancies till September 22nd, 2013.
Please use the Reference Code -EuTRiPD- ESR.
Send the following documents via e-mail to the project manager (t.vanwier@vumc.nl)
• Letter of intent (research interests, reasons for applying to this program and project, respectively);
• A complete CV
• Certified copies of University Diploma or Master certificates;
• Proof of proficiency in English language
• Letters of recommendations (Optional).

NIH-funded Postdoctoral Fellowship Position

NIH-funded Postdoctoral Fellowship Position, to begin after Oct 1, 2013 (duration:
2-5 yrs).
Eukaryotic Cell RNA Metabolism
National Institutes of Health (NIH), Bethesda, Maryland

  The Fellow will investigate molecular mechanisms involved in RNA metabolism
relevant to growth and/or development.  The project structure at the NIH is
flexible such that the right person may be fit to study links between
transcription, RNA processing, nuclear transport, and translation, with particular
emphasis on tRNA and mRNA metabolism.  Fission yeast as well as mammalian cell
culture, and gene-altered mice serve as model systems.  Efforts may include
massively parallel sequencing.  Laboratory approaches integrate cell biology,
molecular biology, genetics, biochemistry and structural biology. 

  Candidates must hold a Ph.D. or M.D. and have less than 5 years postdoctoral
experience.  Expertise in molecular biology, genetics and/or biochemistry is
required, as are strong letters of recommendation.  The successful candidate will
confer regularly with the principal investigator but must incorporate
self-directed research, as well as excellent technical, presentation, and
communication skills as essential parts of the job. 

  The candidate should email a cover letter that details his/her specific interest
in the research areas described above and as reflected by the publications from
the Maraia lab.
Send your cover letter, C.V., and the names of three references with their email
addresses and telephone numbers by Email to: Richard J. Maraia, M.D.  Email:
maraiar@mail.nih.gov    

Richard J. Maraia, M.D.
Captain, US Public Health Service
Chief, Section on Molecular and Cell Biology
Intramural Research Program
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Institutes of Health
31 Center Dr., Rm 2A25 
Bethesda, MD 20892-2426
Phone: 301 402-3567
http://maraialab.nichd.nih.gov/

Oferta plaza predoctoral en la Universidad de Cádiz

Estudiante predoctoral para realización de tesis doctoral
en el campo de la enfermedad de Alzheimer y los
mecanismos que llevan al depósito de beta-amiloide
Requisitos:
- Titulación en Biología, Farmacia, Bioquímica o áreas afines
- Expediente académico competitivo (>2.5)
- Preferentemente con Máster homologado en áreas afines
- Clara vocación científica y dedicación
- Nivel medio-alto de inglés
Contacto:
Dra. Mónica García Alloza
Área de Fisiología
Facultad de Medicina
Universidad de Cádiz
email: monica.garcia@uca.es

PhD Research Project

Deciphering the Role of Global Transcriptional Noise During Rapid Adaptation to Reactive Oxygen Species.

Institution:

Imperial College London

Dept/School/Faculty:

MRC Clinical Sciences Centre

PhD Supervisor:

Dr S Marguerat

Application Deadline:

31 August 2013

Funding Availability:

Competition Funded PhD Project (Students Worldwide)

Gene expression is inherently stochastic due to low copy numbers of genes and mRNAs and to extrinsic fluctuations. Genes that are involved in stress response are particularly noisy and the resulting population heterogeneity is thought to help cells to cope in uncertain environments. Although dynamic gene expression responses in cell populations have been widely studied, we know very little about the cell-to-cell variability in transcriptional programs launched by individual cells in response to environmental challenges, and even less about how this response depends on cell phenotypes such as size or cell-cycle stages.
Oxidative stress resulting from an excess of reactive oxygen species damages components of the cell and is implicated in human diseases such as Alzheimer and cancer. In free living organisms, survival after acute exposure to oxidative agents is ensured by a complex and coordinated gene expression program regulated at the transcriptional and post-transcriptional levels. The fission yeast Schizosaccharomyces pombe is a popular model to study the cellular responses to oxidative stress with many of the pathways involved conserved in multicellular organisms.
In order to understand better the interplay between environmental stress, signalling pathway regulators and stochasticity in gene expression, we offer an interdisciplinary PhD studentship shared between the groups of Dr Samuel Marguerat (Quantitative Gene Expression) at the MRC Clinical Sciences Centre and of Dr Vahid Shahrazaei (Biomathematics) at the department of Mathematics, both affiliated to Imperial College London. If awarded the studentship, you will analyse the dynamic response of fission yeast cells to oxidative stress and exploit the quantitative and single-cell genomics techniques being developed in the Quantitative Gene Expression group to generate measurements of 1) cellular phenotypes such as cell-size and cell-cycle stages, 2) mRNA levels in cell populations, and 3) transcriptional cell-to-cell variability in single cells. You will then use these datasets to develop, in the Shahrezaei group, stochastic mathematical models of oxidative stress signalling. This integrated experimental and computational project will shed light on how stochasticity and global noise in gene expression are affected as a function of cell phenotypes during a dynamic response.
Candidates from both biological and physical sciences would be considered but a clear motivation to develop the skills necessary to pursue both the theoretical and experimental aspects of the project is desired. Programming or computational experience would be an asset. Although a start date in October 2013 would be preferred, applicants interested in starting at a later date will also be considered.
This project will involve techniques such as: yeast genetics and cell biology, RNA-seq, single-cell genomics, microscopy, stochastic modelling of biochemical networks and bioinformatics.

Funding Notes:

These studentships provide a generous stipend (currently £19,000), tuition fees and bench fees for 3.5 years.

This is an Interdisciplinary Cross Campus Collaborative Studentship (ICCS) with joint supervision from Dr Samuel Marguerat and Dr Vahid Shahrezaei. [http://www.csc.mrc.ac.uk/Jobs/PhDStudentship/ICCS/]

Applicants must meet Imperial College entry requirements.

For more information and an application form please follow the Apply Online link on this page.
CVs will not be accepted; you must fill out the application form available on the CSC website.

Interviews will be held at the start of September.

References:

1. Shahrezaei V. et al. (2008) Curr Opin Biotechnol, 19:369-74
2. López-Maury L. et al. (2008) Nat Rev Genet, 9:583-93
3. Sosa V. et al. (2013) Ageing Res Rev, 12:376-90 

more info: http://www.findaphd.com/search/ProjectDetails.aspx?PJID=46385
 

Post-doctoral Position

A fully-funded post-doctoral position is available in the Laboratory of Dr. Pei-Yun Jenny Wu
at the Institute of Genetics and Development of Rennes (IGDR), France. Our laboratory uses
the fission yeast Schizosaccharomyces pombe to investigate the control of DNA replication
and the maintenance of genome integrity. We are seeking candidates to conduct a project that
will focus on the interplay between the program of DNA replication and cellular function.
We welcome all applicants with a solid training in molecular biology and genetics.
Candidates with experience using yeast as a model system are strongly encouraged to apply,
as well as those with a background in cell cycle regulation and DNA replication. This work
will use a combination of methodologies, including genomic (microarray and next-generation
sequencing) and single molecule analyses of DNA replication, as well as high-resolution livecell
imaging. This position is funded by the ATIP-Avenir program of the CNRS/INSERM.
Research at the IGDR covers a wide variety of subjects in the area of cell biology and
genetics, with a strong emphasis on promoting interdisciplinary approaches while taking
advantage of most classical model systems. With 20 teams and approximately 200
researchers, the IGDR provides a dynamic and international scientific environment. The
working language of the laboratory and the institute is English. For more information, please
see: http://igdr.univ-rennes1.fr/english/.
The IGDR is located in the vibrant city of Rennes, the capital of the Brittany region in
northwestern France. Rennes is ideally located for access to Paris (2 hours by train) as well as
to the beautiful coast of Brittany (from 45 minutes by car). With a rich tradition in arts and
culture, Rennes was named in 2012 the city in France where it is the most pleasant to live.
Candidates should contact Dr. Jenny Wu at pei-yun.wu@univ-rennes1.fr. To apply, please
send a letter describing your interest in this research as well as a Curriculum Vitae (CV)
detailing your publications and past research experiences. Applicants should also request
letters of recommendation to be sent directly by two or three referenc

Anuncio de beca predoctoral en el Grupo de Investigación de la URJC

Se ofrece una beca de formación de personal docente e investigador (dos años
beca, con renovación a dos años de contrato) en el grupo liderado por la Dra. Gema Medina
para realizar una tesis doctoral en el Dpto. de Bioquímica, Fisiología y Genética Molecular en
Facultad de Ciencias de la Salud de la Universidad Rey Juan Carlos.
Los candidatos serán preferentemente licenciados en Farmacia, Bioquímica, Biología,
Medicina o en cualquier disciplina de la rama de las Ciencias de la Vida. Expediente académico
superior a 2.5 (escala 1-4), valorándose la formación o experiencia específicas en modelos
animales. Se valorará formación ya realizada en Master o DEA.
El plazo de presentación de solicitudes será, aproximadamente, durante los meses de
Julio y agosto, para iniciar la beca lo antes posible en el mes de Septiembre del 2013. Se espera
que la incorporación al grupo de la persona seleccionada se realice en ese mes y por un período
de hasta 4 años (2+2).
Se buscan candidatos altamente motivados por la investigación e interesados por la
fisiología y biología molecular. El candidato idóneo deberá poseer un buen conocimiento del
idioma inglés, capacidad de trabajo en equipo y facilidad para la comunicación. También motivado
por la docencia en asignaturas relacionadas en Grados de la Facultad de Ciencias de la Salud.
Los interesados deberán enviar un correo electrónico, adjuntando currículum vitae y
expediente académico a:
Gema Medina-Gómez, PhD
Dpto. de Bioquímica, Fisiología y Genética Molecular
Universidad Rey Juan Carlos
Facultad de Ciencias de la Salud
Avda.de Atenas s/n
28922 Alcorcón
Madrid
Spain
tlfno despacho: +34 91 4888632
fax: +34 91 4888831
email: gema.medina@urjc.es

Postdoctoral positions in Ireland

Post-Doctoral Researcher in microRNAs and Neuroscience, Dublin, Ireland


The Centre for the Study of Neurological Disorders at the Royal College 
of Surgeons in Ireland (Dublin, Ireland) is seeking an excellent 
Post-Doctoral Researcher to carry out studies on the role of microRNAs 
in epilepsy. The project will involve identification and functional 
studies on microRNAs and their targets within the brain in experimental 
models and human tissue. Applicants should have a background in 
neuroscience or equivalent discipline, and strong skills with 
human/mouse genetics, biochemistry, molecular biology, cell biology and 
bioinformatics.


Recent publications by the group: Jimenez-Mateos et al. (2012) Nat Med 
18(7):1087-94;

Appointment: The post is available immediately for up to three years. 
Salary is based on experience. Interested candidates are invited to 
submit their CV along with a brief cover letter and names of two 
referees to dhenshall@rcsi.ie <mailto:dhenshall@rcsi.ie> or 
evajimenez@rcsi.ie.


    Post-Doctoral Researcher in Neuroscience, Dublin, Ireland

A Post-Doctoral position is available in the laboratory of Prof. David 
Henshall within the Centre for the Study of Neurological Disorders at 
the Royal College of Surgeons in Ireland (Dublin, Ireland). The project 
will explore the function of small non-coding RNAs including microRNAs 
in experimental models of epilepsy. Applicants should have a background 
in neuroscience or equivalent discipline, and expertise with in vivo 
electrophysiology, animal models, cognition/behaviour, drug delivery and 
histopathology.


Recent publications by the group: Jimenez-Mateos et al. Nat Med 
18(7):1087-94 (2012); Engel et al. Brain 136:577-92 (2013)


Appointment: The post is available immediately for up to three years. 
Salary is based on experience. Interested candidates are invited to 
submit their CV along with a brief cover letter and names of two 
referees to dhenshall@rcsi.ie <mailto:dhenshall@rcsi.ie> or 
evajimenez@rcsi.ie.

Research Fellow in Molecular Biology/Systems Biology

Warwick Biomedical Cell Biology Division/System Biology Centre

£27854 - £33230 (Appointments are usually made on the first point of the salary range)

Fixed Term Contract for 36 months.

Research Fellow in Molecular Biology and statistical analysis of high throughput biological data

You will work on an exciting project unraveling genome wide questions regarding DNA replication in fission yeast. You will join an interdisciplinary team studying the different factors that affect the DNA replication process utilising state-of-the-art molecular biology techniques including next generation sequencing and microarrays.  Your will be expected to use a range of experimental techniques and analyse your data using a variety of statistical and bioinformatic methods in conjunction with modelling collaborators.  The project focus will be on answering key questions using hypothesis testing and model selection techniques.

You will have a PhD in molecular biology or genetics, and ideally be skilled in analysis and integration of large diverse data sets. Previous experience with high throughput sequencing analysis, microarrays and/or Bioinformatic analysis will be an advantage. Experience of writing scientific papers/reports and good communication skills with other disciplines are desirable. You will be working within a collaborative team of experimentalists and theorists, so having an interest in the biological questions is expected.

Please include a full CV and a covering letter with your application form explaining how your skills meet the requirements, what you can bring to the post and why the post interests you.

Enquiries can be made to Dr. Jacob Z. Dalgaard. J.Z.Dalgaard@warwick.ac.uk

The post is funded by BBSRC.

This is an open advert and we fully expect to interview well qualified candidates within a couple of weeks of application. 

Closing date: 7th August 2013.

Posdoctoral position: International Postdoctoral Programme- CNIC IPP 2013 call Spanish National Cardiovascular Research Center (CNIC) Madrid (Spain)

Postdoctoral position is available in the Stress kinases in Diabetes, Cancer and Cardiovascular Disease group, led by Dr Guadalupe Sabio. The project will examine the role of p38MAPK in the development of obesity and obesity-induced diseases (diabetes, cardiovascular diseases, cancer and atherosclerosis). We are looking for enthusiastic and highly-motivated person with an interest in signalling.
Candidates must possess a PhD or MD degree (or equivalent) with experience in molecular biology, cell biology, lipid metabolism, signalling and animal models. A strong publication record will be valued.
For more information see: http://www.cnic.es/en/inflamacion/quinasas/index.php
Eligibility:
- PhD awarded later than 31st August 2008 (additional years for children or career breaks)
- Translational mobility: residence in Spain less than 12 months in the last three years.
- At least one first author publication in an international peer reviewed journal.
Applications for CNIC-IPP are accepted exclusively online through our online application system. The 2013 call will be open until the 31st of August.
Qualified applicants should also submit by e-mail, a CV, a letter outlining research interests, and the contact information of three referees, to Guadalupe Sabio: gsabio@cnic.es

Beca de Formación de Personal Investigador (FPI) en CISA-INIA

Se busca candidato/a para SOLICITAR un contrato predoctoral de Formación de Personal Investigador (FPI) en la convocatoria 2013, asociado al proyecto: MECANISMOS DE MODULACION DE LA RESPUESTA A IFN-I POR EL VIRUS DE LENGUA AZUL (BTV) Y PESTE DES PETITS RUMINANTS (PPRV).

El proyecto contempla el estudio de los distintos mecanismos desarrollados por BTV y PPRV para evadir la respuesta a IFN-I.

Se requiere un mínimo de 2 en el expediente académico en Biología, Farmacia, Bioquímica, Veterinaria, Medicina o titulaciones afines.

Se valorará experiencia previa en laboratorios en el campo de la inmunología y biología molecular, así como manejo de animales de experimentación, y haber realizado un máster.

La incorporación se realizaría en el Centro de Investigación en Sanidad Animal (CISA-INIA), en el grupo de Respuesta Inmune Frente a Enfermedades Relevantes en Sanidad Animal bajo la supervisión de la Dra. Noemí Sevilla.

Interesados mandar un CV a sevilla@inia.es

PhD opportunities

PhD scholarships are available for talented students interested in studying the interactions between phages and bacteria.
The overarching theme of our research is the interactions between bacteria and their bacteriophages with a major focus on CRISPR-Cas and abortive infection/toxin-antitoxin resistance mechanisms (http://micro.otago.ac.nz/research/research-labs/fineran-lab-research). Our research utilises molecular genetics, bioinformatics, biochemistry and structural biology to gain molecular insight into phage-host biology. A number of PhD projects are available in CRISPR-Cas bacterial immunity, toxin-antitoxin/abortive infection systems and the use of phages as antimicrobial agents. The group has a strong track record in these areas and the positions will provide the student with excellent opportunities to build their scientific career in these exciting areas.

The University of Otago is one of the top research universities in New Zealand and includes excellent facilities available for our research (e.g. genome sequencing, proteomics, microscopy etc.). The Department of Microbiology and Immunology has recently been refurbished and the Fineran laboratory is new (2012) and well equipped. The group actively collaborates with researchers within the University, New Zealand and internationally. There is an thriving post-graduate community within the department (http://micro.otago.ac.nz/research/postgrad-research).
The successful candidate will hold a BSc(Hons) or MSc in Molecular Microbiology, Biochemistry, Genetics or a related discipline and be highly motivated about research. If interested, please contact Dr Peter Fineran providing an explanation of your interest in the project, a CV and details of 2-3 academic referees (peter.fineran@otago.ac.nz). Please include a copy of your full academic transcript (and if applicable) an explanation of content. Starting dates are flexible.

Funding:

The PhD position requires the applicant to be eligible for admission to the PhD programme at the University of Otago and to be eligible for a scholarship (http://www.otago.ac.nz/study/scholarships/index.html). A GPA of 7.5 or greater and demonstration of proficiency in English are essential.

Funding for the PhD scholarship is NZ$25,000 pa for three years. This scholarship is tax free and tuition fees are waived.
International PhD students pay tuition fees at the New Zealand domestic rate, provided that the students reside in New Zealand and study under a New Zealand student visa.

FPI contract for PhD Thesis in WIRING of NEURAL CIRCUITS

MINECO’s latest communication: application deadline SEPTEMBER 10th 2013
Join us study how neurons select and establish connections with their
appropriate synaptic partners, under the research project BFU2012-32282:
“Genomics and Genetics of Synaptic Specificity” funded by MINECO. We
address synaptic specificity by studying two closely related neurons that differ in
their connectivity: the R7 and R8 photoreceptors of the fly eye. Our previous
work revealed cell specific transcription factors regulating R7 and R8 wiring.
Using RNAseq, we have identified differentially expressed genes between these
two neurons. We are gearing up to test the requirement of differentially
expressed candidate genes and to characterize the transcriptional network
regulating their expression.

Requisites: - Degree in Biology, Biomedicine, Biochemistry or related
- Grades above 2
Interested students send ASAP: - CV with contact information for references
- Academic record
- Letter of interest
to Dr. Marta Morey (mmorey@ub.edu) Ramon y Cajal Researcher
Universitat de Barcelona, Departament de Genetica,
http://www.ub.edu/genetica/desenvolupament/moreyre.htm
Morey, M.*, Yee, S.K.*, Herman, T., Nern, A., Blanco, E. & Zipursky, S.L. Coordinate control of synapticlayer
specificity and rhodopsins in photoreceptor neurons, Nature. 2008 Dec 11;456(7223):795-9.
Pappu, K. S., Morey, M., Nern, A., Spitzweck, B., Dickson, B.J. & Zipursky, S.L. Robo-3 mediated
repulsive interactions guide R8 axons during Drosophila visual system development, Prot. Natl. Acad.
Sci. 2011 May 3; 108(18): 7571-7576.