Position available for application to the Spanish MINECO Postdoctoral Programme

Centro Nacional de Investigaciones Cardiovasculares Department of Epidemiology, Atherothrombosis and Imaging Position available for application to the Spanish MINECO Postdoctoral Programme (2+2 years, BOE 313, December 31, 2013, page 107239) Eligibility criteria: • Doctoral thesis defended not before September 1, 2009 (but see exceptions in BOE), and predoctoral training not in CNIC • PhD degree must be hold at a date before of or coinciding with the publication of MINECO’s decision (possibly in June 2014) • Candidates cannot be recipients of Ramón y Cajal or Juan de la Cierva contracts from previous years, and cannot apply to the Ramón y Cajal Program this year. Moreover, they can only apply for 1 research center • Particularly valued will be experience in molecular/cellular biology and in animal models of cardiovascular disease and/or aging, as well as first author publications in international peer-reviewed journals The project will be carried out in the Molecular and Genetic Cardiovascular Pathophysiology Laboratory (Dr. Vicente Andrés, http://www.cnic.es/en/imagen/fisiopatologia/index.php). We investigate the mechanisms that underlie atherosclerosis and vascular calcification and how aging contributes to these anomalies. We are particularly interested in the role of A-type lamins (lamin A/C) on cardiovascular disease and aging, including Hutchinson-Gilford progeria syndrome (HGPS), a premature aging disease that recapitulates key aspects of physiological aging. Our experimental strategy involves a multifaceted approach that combines in vitro, cellular, animal and human studies and a variety of technologies including mouse genetic engineering, proteomics, transcriptomics, FRET, intravital microscopy, non-invasive imaging, confocal microscopy, etc. Selected publications of the group: •Chèvre, R. et al. Circ Res (in press) •Villa-Bellosta, R. et al. Circulation. 2013 •Trigueros-Motos, L. et al. Arterioscl Thromb Vasc Biol. 2013 •Rivera-Torres, J. et al. J Proteom. 2013 •Fuster, JJ. et al. Arterioscl Thromb Vasc Biol. 2011 •González, JM et al. J Cell Biol. 2009 •Ivorra, C. et al. Genes & Dev. 2006